An International Journal for Oncology Research.  

 


May 2008
Volume 10, Number 5
Cover Illustration:
The cover is an artistic depiction of an immunohistochemical comparison of K-Ras and Raf-1-induced tumors in Ntv-a;Arf-/- mice. Representative immunohistochemical patterns of each tumor type are illustrated.

TABLE OF CONTENTS

Research Article

Integrin a6b4 promotes migration, invasion through Tiam1 upregulation and subsequent Rac activation
Zobeida Cruz-Monserrate and Kathleen L O'Connor
Abstract   Full Article

Inhibition of apoptosis in prostate cancer cells by androgens is mediated through down-regulation of c-Jun N-terminal Kinase activation
Petra Isabel Lorenzo and Fahri Saatcioglu
Abstract   Full Article

In vivo confocal fluorescence imaging of the intratumor distribution of the photosensitizer mono-L-aspartylchlorin-e6 (NPe6)
Soumya Mitra and Thomas H Foster
Abstract   Full Article

Prostate cancer cell-derived urokinase-type plasminogen activator (uPA) contributes to intraosseous tumor growth and bone turnover
Zhong Dong, Allen D Saliganan, Hong Meng, Sanaa M Nabha, Aaron L Sabbota, shijie sheng, R Daniel Bonfil and Michael L Cher
Abstract   Full Article

Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells.
Damian J Junk, Lukas Vrba, George S Watts, Marc M Oshiro, Jesse D Martinez and Bernard W Futscher
Abstract   Full Article

Activation of map kinase signalling via ERK5 but not ERK1 expression is associated with lymph node metastases in oral squamous cell carcinoma (OSCC)
Carsten Sticht, Kolja Freier, Karl Knöpfle, Christa Flechtenmacher, Susanne Pungs, Hofele M Christof, Meinhard Hahn, Stefan Joos and Peter Lichter
Abstract   Full Article

Decitabine induced demethylation of 5’ CpG-island in GADD45A leads to apoptosis in osteosarcoma cells
Khaldoun Al-Romaih, Bekim Sadikovic, Maisa Yoshimoto, Yuzhuo Wang, Maria Zielenska and Jeremy A. Squire
Abstract   Full Article

Cathepsin B mediates the pH dependent proinvasive activity of tumor shed microvesicles
ilaria giusti, Sandra D'Ascenzo, Danilo Millimaggi, Giulia Taraboletti, Gaspare Carta, Nicola Franceschini, antonio pavan and vincenza dolo
Abstract   Full Article

Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors
Toshio Kuwai, Toru Nakamura, Takamitsu Sasaki, Sun Jin Kim, Dominic Fan, Gabriel J Villares, maya zigler, Hua Wang, Menashe Bar-Eli, Robert S Kerbel and Isaiah J Fidler
Abstract   Full Article

Constitutive activation of Raf-1 induces glioma formation in mice.
Yelena Lyustikman, Hiroyuki Momota, William Pao and Eric C Holland
Abstract   Full Article

Bevacizumab inhibits breast cancer induced osteolysis, surrounding soft tissue metastasis and angiogenesis in rats as visualized by VCT and MRI
Tobias Bäuerle, Heidegard Hilbig, Sönke Bartling, Fabian Kiessling, Astrid Kersten, Annette Schmitt-Gräff, Hans-Ulrich Kauczor, Stefan Delorme and Martin R Berger
Abstract   Full Article

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